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This selective mechanism has made it a focus of research in obesity, fat metabolism, and cartilage repair, offering a more targeted metabolic profile without the systemic hormonal effects associated with growth hormone.

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British Journal of Nutrition, 135 (9), 956963

Whether the 7-mer recapitulates full-T4 activity in corneal, cardiac, or other indications has not been independently established in the published literature

IGF-I Enhances Cellular Senescence via the Reactive Oxygen SpeciesP53 Pathway