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These include model phenotyping studies and the characterization of several MASH-targeted drug classes, such as GLP1R agonists (e.g., semaglutide), THR- receptor agonists (e.g., resmetirom), PPAR agonists (e.g., lanifibranor), FGF21 analogues (e.g., efruxifermin), as well as various long-acting dual GLP1R-GIPR agonists (e.g., tirzepatide) and GLP1R-GCGR agonists (e.g., survodutide)
Goodman T, Hajihosseini MK
Eating is a common coping strategy people use to deal with stress, depression , or anxiety
Patients with certain FTO and MC4R variants often achieve superior results with dual-agonist therapy rather than single-compound approaches