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Tirzepatide can be effective for weight management in steroid-treated patients, though the metabolic environment created by corticosteroids, including insulin resistance, increased appetite, and altered fat distribution, may affect the magnitude of response
GLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R
Liau JY, van Aalst JA, Sadove AM
No validated outcome measures
But the reason it does not is genuinely interesting, and it comes down to bioavailability the fraction of a swallowed dose that actually reaches your bloodstream
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