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The role of endogenous incretin secretion as amplifier of glucose-stimulated insulin secretion in healthy subjects and patients with type 2 diabetes
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Our experiment enabled us to test this hypothesis by measuring insulin secretion in response to glucagon bolus in the presence or absence of exendin 9-39
Nat Rev Immunol 23(11):735748
Lipid peroxidation, created by free radicals attacking cell membranes, results in the production of lipid peroxidation derivatives, including 4-HNE, MDA, and many other toxic aldehydes.[] HNE can damage beta cells of the pancreas and impair the ability of muscle and the liver cells to respond to insulin
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