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Source Data Extended Data Fig
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Semaglutide's effect on appetite and metabolic rate is dose-dependent and cumulative over weeks, so a single week of lower levels typically doesn't erase weeks of therapeutic benefit
Results Development and characterization of roGFP2-iL To investigate whether roGFP2 can be modified to generate less reducing probe variants, the roGFP2 sequence was further engineered by introducing site-specific mutations thus generating roGFP2-iL (Figures 1A,B)
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