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ABC transporters (ATP-binding cassette) specially P-gp (P-glycoprotein) play an important role in clinical drug resistance by many of mechanisms for example high level expression by gene rearrangement

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There will be minimal effects on insulin and glucagon production, as both are already significantly impaired in type 1 diabetes, and slowing gastric emptying is not an obvious advantage

They also provide a support system and someone who can hold you accountable to encourage you to take the best possible care of your body and get to a point where your weight is attainable and manageable

So it really came because of support from other scientists