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AT1R expression in mesangial cells and podocytes, induced by high glucose levels, promotes intracellular expression of profibrotic and pro-inflammatory mediators, such as transforming-growth factor beta (TGF- ), vascular endothelial growth factor (VGEF), and interleukin-6 (IL-6) leading to hyperplasia and hypertrophy, mainly of the proximal tubule, together with extracellular matrix production (34)

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Research supporting GLP-1 receptor agonist therapy demonstrates that adherence to the prescribed regimen is strongly associated with improved HbA1c reduction and sustained weight management benefits

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Research from the Endocrine Society presented in their latest findings showed that higher protein intake directly correlated with better muscle preservation during GLP-1 therapy