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The American Diabetes Association (ADA) recommends GLP-1 receptor agonists with proven cardiovascular benefit as preferred agents for patients with type 2 diabetes who have established atherosclerotic cardiovascular disease or indicators of high cardiovascular risk
References: Friedrich, M
JMJD3 demethylation of these promoters de-represses target autophagy genes, which in turn restores functional autophagy and lipid catabolism in obese animals
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These fatty acids have been shown to increase GLP-1 secretion in the colon
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