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Unlike semaglutide, tirzepatide targets both GLP-1 and GIP (gastric inhibitory polypeptide) receptors, enhancing fat metabolism and insulin sensitivity
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One meta-analysis of nine studies published in Cancer Medicine showed that people who used Actos had a significantly higher risk of bladder cancer after more than two years of use (when compared to those who had never used Actos) This led the FDA to add a bladder cancer warning to the drugs label in 2011
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While a GLP-1 might help their binge eating behaviors, it could also be gas on the fire of other disordered eating habits
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