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Primarily through its antioxidant, anti-inflammatory, and glutamate modulation activity, NAC has been investigated in the treatment of neurodevelopmental disorders, schizophrenia spectrum disorders, bipolar-related disorders, depressive disorders, anxiety disorders, obsessive compulsive-related disorders, substance-use disorders, neurocognitive disorders, and chronic pain
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Subgroup analysis according to IBS subtypes (e.g., IBS-C, IBS-D, IBS-M, and IBS-U) would have offered significant insight on how the intervention differed in its effects on these various patient groups
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