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For example, the OASIS-4 trial showed an average weight loss of 13.6% with the maximum 25 mg dose, which takes 4 months to reach under the licensed dosing protocol
Alternative pharmacological options with established safety profiles include: Semaglutide (Wegovy): Another GLP-1 receptor agonist with robust weight loss data and cardiovascular risk factor improvements (with cardiovascular outcome benefits demonstrated in the SELECT trial) Liraglutide (Saxenda): Daily GLP-1 agonist injection licensed for weight management Orlistat: Lipase inhibitor that reduces dietary fat absorption, available over-the-counter or on prescription Each has distinct side effect profiles and may suit different patient populations
E., Beckel, J
he duration of the program may vary based on individual goals and progress
Carillo, M
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