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Preclinical work on optimized tri-agonists demonstrates "best-of-both-worlds" profiles, achieving greater energy expenditure and deeper weight normalization than GLP-1-only comparators [4]
Biochem/physiol Actions Melanotan II is a MC3-R/MC4-R melanocortin agonist
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doi:10.1136/gutjnl-2014-308778 Wang Y, He J, Chen S, et al
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