In the analysis that most closely reflects real-world clinical practice, participants taking oral semaglutide lost an average of 13.6% of their starting body weight, compared with just 2.4% in those receiving placebo
Heart rate typically settles to a level modestly above baseline but well below the week 24 peak
For others, it could mean staying on the lowest dose of a GLP-1 medication instead of gradually increasing, deviating from what the clinical trials indicate is needed for weight loss and lower than the doses approved for weight maintenance by the FDA, says Nidhi Kansal, MD , an internal medicine specialist at Northwestern Medical Group
Direct answer: It improves metabolic health while in use
Because GLP-1 drugs are serious medicines that carry risks as well as benefits, it is best to obtain a prescription from your doctor or a health professional you know