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Large clinical trials including LEADER, SUSTAIN-6, and EXSCEL have not identified increased fracture rates with GLP-1 therapy compared to placebo
Some patientsparticularly those with treatment-resistant vertex thinning or diffuse thinningrespond better to higher concentrations (6%, 8%, or even 10% in some compounded formulations)
Supports healthy brain and cognitive function
Some reports associate MDD to increased levels of cytokines including TNF, IL-6, and IL-1, as well as a reduction in complement C3 (4749)
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