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injectable use carries added risks of injection-site irritation, and systemic use should be avoided during pregnancy since copper crosses the placenta and no controlled human pregnancy data exists
doi: 10.1136/bmj.g2366 59 WentenMGaeblerJAHusseinMPelletierEMSmithDBGirasePet al
A: Lipohypertrophy is the formation of fatty, fibrous lumps under the skin resulting from repeated injections in the same location
Additionally, the ghrelin receptor is abundantly expressed in somatotrophs of the pituitary gland, supporting the role of ghrelin in regulating GH release
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