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Product quality is a major confounder: research-grade material sold "for research use only" is not manufactured to pharmaceutical standards, and contaminants, incorrect concentrations, or endotoxins can cause harms that have nothing to do with the peptide itself

As of now, research on small molecule GLP-1RAs is still mainly in the laboratory and early clinical trial stages

The specific activity was calculated from the final protein concentration (1.3 nM g protein -1 min -1 ) in the reaction mixture

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