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Other indicators include a family history of pernicious anaemia or other autoimmune conditions (such as type 1 diabetes mellitus, Hashimotos thyroiditis, or Graves disease), or if the patient is taking metformin, proton pump inhibitors (PPIs), H2 antagonists or has a history of nitrous oxide misuse[15]

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Despite these benefits, long-term LC administration has been associated to cardiovascular risks due its conversion to trimethylamine- N -oxide (TMAO) by the gut microbiota

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therefore, the therapeutic use of SOD and SOD-mimetics (e.g., Mangafodipir ) may prove beneficial in PASC recovery 565,569

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Our APAP model [10] is simple because it does not include the processing of GSH in the mitochondria that has been shown to be fundamental for liver cell death in the presence of APAP [36]

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