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doi: 10.3389/fcell.2025.1697843 Received 02 September 2025 Revised 04 November 2025 Accepted 08 December 2025 Published 19 December 2025 Volume 13 - 2025 Edited by Hehuang Xie, Virginia Tech, United States Reviewed by Lin Liu, Nankai University, China Viski Hendrawan, Brawijaya University Hospital, Indonesia Updates Copyright 2025 Derrico, Scaturro, Murray, Guillen, Truss, Fairly, Higgins, Bhadsavle and Golding
10.3390/ijms18122645 112
Neither body of evidence is sufficient to support clinical recommendations
GHK-Cu contributes to redox balance and extracellular matrix homeostasis by stimulating metalloproteinase activity and increasing antiprotease expression, while also participating in the regulation of copper-dependent antioxidant enzymes
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