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For example, ALCAR is needed for cell membrane functions, neurotransmission, essential fatty acid metabolism, energy metabolism, and antioxidant protection (Pettegrew et al., 2000)

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Natural ghrelin is only active at GHS-R1a when it carries a specific fatty-acid modification an octanoyl (C8) group attached to its third amino acid by the enzyme ghrelin O-acyltransferase (GOAT)