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Taken together, the metabolic actions of GLP-1 and glucagon, as well as their structural similarities, inspired the search for single-molecule GLP-1R/GcgR co-agonists as potential candidates for obesity treatment

Currently prescribed an intervention and current status is marginal therefore advisable to monitor status

Should Patients Stop GLP-1 Therapy Before Testing

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Similarly, as seen in non-syndromic obesity (43, 44), semaglutide treatment discontinuation, which occurred in Patient 1 and Patient 2, resulted in weight regain