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The primary safety consideration with GLP-1 receptor agonists before colonoscopy centers on pulmonary aspiration during sedation
use in perimenopause or postmenopause is off-label and should be evaluated with a licensed provider
Corticosteroid pulses: If you need high-dose steroids for an MS relapse, these may temporarily offset Wegovys glucose-lowering effects
According to NICE guideline NG28, GLP-1 receptor agonists should be considered when: Triple therapy (metformin and two other oral drugs) is not effective, not tolerated, or contraindicated The patient has a BMI 35 kg/m (or lower in people of Black, Asian and other minority ethnic groups) and specific obesity-related comorbidities The patient has a BMI 40% reduction in non-HDL cholesterol GLP-1 receptor agonist for glycaemic control and weight management (with secondary lipid benefits) Ezetimibe if non-HDL cholesterol reduction is insufficient Lifestyle interventions addressing diet, exercise, and weight Monitoring and follow-up are essential components of cholesterol management
10.1111/j.1749-6632.1987.tb23750.x Ann N Y Acad Sci
