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The results observed a decrease in the amount of expression of COX- 2, TNF-, IL-1, and IL-6 in all groups given the 1.3 bis( p -Hydroxyphenyl)urea and diclofenac sodium compared to the control group CMC sodium 0.5%
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Local injection (near the injury site) delivers maximum concentrations directly to damaged tissue
Applying GHK-Cu or AHK-Cu immediately after microneedling delivers the peptide directly into the dermal layer where target cells reside
Reviewed by FDA against compounding inclusion in December 2024
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