Pay in 4 interest-free payments of $5.28 Learn more
Ships within 48 hours · Estimated delivery Aug 24 - Aug 29
The compound is supplied to laboratories as a lyophilised (freeze-dried) white powder for reconstitution before in vitro research use
This reflects its different chemical nature as a small molecule rather than a peptide
DOI: 10.1007/s00441-019-03016-8
How it works: GHRH receptor binding: Sermorelin binds pituitary somatotroph GHRH receptors, activating adenylyl cyclase and increasing intracellular cAMP to trigger synthesis and pulsatile release of endogenous GH IGF-1 upregulation: elevated GH drives hepatic IGF-1 production, which mediates the downstream anabolic effects including lean mass accretion, bone density support, and tissue remodeling Preserved feedback regulation: because sermorelin works through the hypothalamic-pituitary axis rather than bypassing it, natural somatostatin-mediated negative feedback remains intact, reducing the risk of GH excess seen with exogenous HGH Extracellular matrix support: preclinical models suggest GH axis stimulation may reduce inflammatory cytokine signaling and promote extracellular matrix remodeling, contributing to faster soft tissue recovery Administration: Subcutaneous injection (intramuscular also used) Typical dosing range: 200-500 mcg once daily, most protocols use 300 mcg nightly
Weight loss reduces the production of these cytokines, lowering overall inflammation levels
US$ 23.48
US$ 29.73
US$ 29.65
US$ 24.49
US$ 22.92
US$ 27.06
US$ 23.54
US$ 23.42
US$ 24.58
US$ 23.77
