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Additionally, emerging evidence suggests that chronic systemic oxidative stress, inflammation, and insulin resistance contribute to neuroinflammation and neuronal damage, increasing the risk of Alzheimers disease (Patel and Edison 2024)

Liraglutide has also been shown to significantly reduce overall energy intake and the consumption of all macronutrients, including carbohydrates, protein, and fat during controlled buffet settings (Quast et al., 2021)

The deficiency of vitamin B12 is also known to increase the risk of heart attack and stroke

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However, the guidelines give increasing prominence to GLP-1 receptor agonists and SGLT2 inhibitors for patients with cardiovascular or kidney disease, even at early stages of diabetes