Useful safety observations often include: Local tolerance: redness, irritation, swelling, or tenderness at the administration site Acute post-dose observations: changes in behavior, appetite, activity, or visible discomfort during the expected response window Pattern effects over time: whether repeated dosing appears to change tolerability or response consistency Protocol drift: missed timing windows, inconsistent preparation, or undocumented deviations that can confuse safety interpretation How dosing logic affects safety interpretation The why behind dosage matters most
So my advice, hang in there, take injections with folate etc too
Calcium ipodate is no longer widely available
Because many of these molecules cant be patented, pharmaceutical companies have little reason to fund those trials
The review notes, however, that the degree to which these benefits are independent of weight loss may vary by condition, and further research is needed to elucidate these mechanisms fully