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400 AMPK also induces mitochondrial biogenesis via PGC-1 phosphorylation and SIRT1 activation
Simultaneously, some tumor cells, owing to specific mutations, elevated ROS levels and other unique biological features, exhibit ferroptosis susceptibility, with their survival hinging on the ferroptosis defense system (108)
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Furthermore, there are no published trials specifically evaluating intranasal delivery of BPC-157 in humans
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