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Metabolic improvements during semaglutide treatment phase from timepoint 1 to timepoint 2 included a statistically significant decrease in total and LDL cholesterol, fasting plasma glucose, and glucose on 120 min of OGTT
Losing weight too quickly could be a red flag for muscle loss and bone mineral density
This is referred to as leaky gut
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While not yet tested in surgical patients, there is a related drug Dapansutrile (OLT1177) an orally active NLRP3 inhibitor which is in trials for gout and heart failure
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