Research peptides in this space fall into two distinct mechanistic categories: GHRH analogs (e.g., CJC-1295, Sermorelin, Tesamorelin ) bind the GHRH receptor on pituitary somatotrophs to directly stimulate GH synthesis and release GHRPs / Ghrelin mimetics (e.g., Ipamorelin, GHRP-2, GHRP-6, Hexarelin) bind the GHS-R1a receptor to amplify GH release through a separate, complementary pathway Ipamorelin falls firmly in the GHRP/ghrelin mimetic category
Well, for glutamine it is clearly helpful for gut health
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Combining the two activates GHRH and ghrelin receptors simultaneously a 2-3x greater GH pulse than either alone (Bowers et al., JCEM 1991)
So who should consider trying these medications