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Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, affects gastric emptying by slowing the movement of food through the stomach
The Evidence Gap Despite this popularity, human evidence remains extraordinarily limited
GLP-1 receptors are expressed in pancreatic islet cells, the gastrointestinal tract, vagal afferents, and brain regions involved in satiety and energy balance
Determining if a causal link exists between elevated, synchronized beta-band oscillations and PD motor symptoms, as well as probing how DBS relates to therapeutic outcomes, requires a new kind of neuromodulation tool that can detect and precisely control oscillatory activity in the brain in real time without using high-frequency stimulation
& Zechner, R
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