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(2004) "Inhibition of ghrelin action by an RNA-based GHS-R antagonist." Published in PNAS

Mean levels were 2,100322 mol/l before treatment, 2,095310 mol/l after 1 month (P=0.52), 2,152390 mol/l after 3 months (P=0.43) and 2,120385 mol/l after 6 months (P=0.28

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In contrast, re-expression of MAPKAPK2 reversed these alterations, restoring Nrf2 nuclear localization and enhancing HO-1 expression (Figure 7D), consistent with activation of an antioxidant defense response