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while significant pharmacokinetic interactions with psychiatric medications are not generally expected, GLP-1 agonists may affect absorption of some oral medications due to delayed gastric emptying Discuss realistic expectations regarding weight loss and diabetes control to avoid disappointment that might affect mood Ensure adequate support systems are in place, including regular contact with healthcare providers Discuss pregnancy plans as these medications are not recommended during pregnancy or breastfeeding

Mechanistic studies indicated that these effects were not driven by acute insulinotropic activity, but by -cell preservation and enhanced glucose uptake

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Glutathione may be obtained from an yeast or synthetically