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Changes in insulin sensitivity are another factor involved in PPHG
Diabetes Obes Metab 18(4):317332 Madsen LW, Knauf JA, Gotfredsen C, Pilling A, Sjgren I, Andersen S et al (2012) GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation
Some people cannot tolerate the medication, have health conditions that make it unsuitable, or need a different approach
But by the time you reach a steady maintenance dose, your body may have already adjusted to the medication, which means symptoms may be milder or happen less often
Persistently heavy bleeding (more than 80 mL per cycle, soaking through a pad or tampon hourly) should be evaluated regardless of GLP-1 use
