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New York explicitly requires an in-person medical evaluation before prescribing any controlled substance to a patient, with only narrow exceptions (10 NYCRR 80.63, amended May 2025) (www.cchpca.org)

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In Eli Lilly's Phase 2 clinical trial (published in the New England Journal of Medicine, 2023), 338 adults with obesity or overweight (without diabetes) were treated with retatrutide for 48 weeks

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