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The purity figure printed on each batch's Certificate of Analysis is the actual value recorded in the laboratory for that batch, not a generic marketing claim
Results from a phase 1 trial have supported further clinical evaluation with a dose-dependent WL up to 14.5% with AMG133 compared to 1.5% with placebo by day 85 [59]
The mechanism involves inhibition of the NF-B signaling pathways, a central regulator of genes involved in inflammation (Figure 3)
PMID: 75 HuYYuJXuZGaoYLiYLiL
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