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The treatment backbone is 2-agonist replacement: oral or transdermal clonidine, often at doses above standard labeled recommendations
a BMI of 27 or higher qualifies only alongside pre-diabetes, a previous heart attack, a previous stroke, or symptomatic peripheral artery disease
When that happens, one major risk is that the compounding pharmacy peptide boom will outpace the FDAs ability to monitor them
In the initial semaglutide weight loss trial, 14% of patients lost less than 5% of body weight and 31% lost less than 10%
Matt Mahowald, a veteran LA nutritionist whose A-list clients include Chris Pine, Mandy Moore and Guns N Roses guitarist Slash, says some patients taking GLP-1s report being nauseated by the very prospect of food itself
