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Repositioning curcumin from a generic botanical supplement to an evidence-based immunometabolic adjunct anchored in standardized preparations, pharmacokinetic validation, and clinically meaningful outcome assessment is both scientifically justified and clinically imperative
Studies like the STEP trials (Semaglutide Treatment Effect in People with Obesity) have demonstrated that patients can lose 5-15% of their body weight over several months, with potential for long-term maintenance
Machado AP, Costa Rosa LF, Seelaender MC
Role of nitric oxide in pathogenesis of herpes simplex virus encephalitis in rats
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