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No claims regarding safety or efficacy in living subjects have been evaluated by the FDA or other regulatory agencies
However, high-dose niacin (as a medication for cholesterol) is generally not recommended during breastfeeding, because significant amounts could enter milk and cause unwanted effects in the nursing infant (flushing, for example)
Some users report subtle increases in energy levels, reduced appetite, or slight improvements in how clothing fits during this initial phase
A slow, steady injection allows the B12 solution to disperse in the tissue, leading to better absorption
The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)
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