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It slows down the central nervous system and is one of the leading causes of death in the US

Some studies suggest modest improvements in joint pain and possibly cartilage markers in people with mild knee osteoarthritis

User experimentation suggests that longer initial treatment periods (6+ months continuous) support better benefit retention during subsequent breaks, complete discontinuation breaks of 1-2 months show acceptable benefit maintenance for most users, and very extended breaks (3-6+ months) increase risk of regression toward pre-treatment baseline particularly for short initial treatment courses

10.1200/JCO.19.02492 275 TeperinoR.SchoonjansK.AuwerxJ