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Further research has identified that one of its most notable primary effects is its crucial role in promoting muscle hypertrophy by increasing protein synthesis and nitrogen retention
A nice feature of knowing your TDEE is that it gives you a reference point for instance, you might realize Oh, my maintenance is ~2500, so eating 3000 is a few hundred extra per day. Using that knowledge, you can adjust your meal portions or add a healthy snack or protein shake to hit the surplus
Lack of safety data remains the fundamental concern
Investigating the relationship between IGF-I, IGF-II, and IGFBP-3 concentrations and later-life cognition and brain volume
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