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And like all transformations, it comes with fire
With a ketogenic diet, 60-80% of calories are from healthy fats, 20-30% are from protein sources, and 5-10% are from net carbs (total carbs minus fiber)
Using in silico design, structureactivity relationships (SARs), chemical optimization, cell-based assays and in vivo experiments, we identified and characterized the first-in-kind small-molecule inhibitors of STX7Munc13-4-dependent endosomal maturation and signaling for use in immune cells that contribute to systemic inflammation
Brydges NM, et al
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