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Tirzepatide population pharmacokinetics and exposure Schneck 19-study pooled popPK (CL/F 0.061 L/h, half-life 5.4 d, accumulation 1.7x, body-weight covariate +22% at 70 kg / -33% at 120 kg)
PMC 8716657
This means that the body will remove excess B12 and it cannot reach toxic levels
Research shows that untreated vitamin B12 deficiency can lead to anemia or irreversible nerve damage, making proper diagnosis and treatment crucial
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