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3 Expert Rev Clin Pharmacol Afamelanotide (CUV1647) in dermal phototoxicity of erythropoietic protoporphyria (Minder & Schneider-Yin, 2014)Reviews the -MSH receptor-mediated mechanism, the rationale for afamelanotide in protoporphyria, and the phase II/III and safety results, concluding the risk-benefit profile is favorable in this indication
Metformin is generally considered the first-line choice for managing prediabetes and preventing progression to type 2 diabetes
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