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The researchers highlighted silymarin's liver-protective effects in cases of drug-induced liver injury, fatty liver disease (both alcoholic and nonalcoholic), and alcoholic cirrhosis, attributing successes to the compound's ability to prevent cytotoxicity by reducing oxidative stress on the liver.3 Many of the studies covered in the review administered 420mg of silymarin per day

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Life Sci, 88 (11-12) (2011), pp

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Use of flow cytometry and monochlorobimane to quantitate intracellular glutathione concentrations in feline leukocytes