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Safety: No toxic dose has been determined to date Study in rats with a single 20mg/kg IM dose, no deaths, abnormalities in body weight, food intake, or behavior noted Study in dogs at 10mg/kg IM showed no adverse effects Study in rats of 28 days of 0.2 mg, 1mg, or 4mg/day IM no changes relative to saline injection Study in dogs of 0.1 mg, 0.5 mg, or 2 mg/day IM no changes relative to saline injection Uses: Study: protection against NSAID and alcohol adverse effects Study: healing actions on wound and injuries from trauma and systemic issues Study: benefits in neuropsychiatric conditions like depression, though other studies show it has poor penetration of the blood brain barrier
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It's a tripeptide, meaning it's formed from three amino acids
10.1038/srep00667 Sci Rep
Notably, catheter-based coronary delivery was shown to be safer and more effective, aligning better with current clinical practices
