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Epigenetic modifications such as: DNA methylation and histone acetylationadd an additional layer of adaptive plasticity, potentially enabling stress memory

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In a new study reported in The Lancet, Tirzepatide, a GLP-1R/GIPR agonist, reduced alcohol's rewarding properties, locomotor stimulation, conditioned place preference, and accumbal dopamine release

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Yes, many patients notice reduced cravings and fewer food noise thoughts, which can help reshape eating habitsbut long-term success still depends on behavior and mindset changes