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Many patients on semaglutide or tirzepatide consume far less than this because their appetite is so suppressed

Obeticholic acid (OCA): OCA (Intercept Pharmaceuticals, New York, NY, USA) is a farnesoid X nuclear receptor (FXR) ligand that is currently being evaluated in the phase 3 study REGENERATE (NCT02548351) for the treatment of NASH

Nausea and vomiting can be treated by : drinking small amounts of fluid often (mainly water or electrolyte drinks) eating small, plain meals, if you can avoiding rich, fatty, or greasy foods avoiding caffeine, sugary drinks, or alcohol avoiding smoking, if you smoke, especially on an empty stomach getting fresh air resting distracting yourself when you feel nauseous to try and get your mind off of it, such as reading or watching your favourite TV show using over-the-counter or prescription medicines, such as anti-sickness tablets, after speaking with a pharmacist or doctor taking your Mounjaro dose with food, as this may alleviate some of the symptoms As with diarrhoea, introduce foods back slowly as you start to feel better

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