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Serious but less common risks include pancreatitis, gallbladder disease, worsening of diabetic retinopathy, kidney injury related to dehydration, and rare severe allergic reactions

Recent supplementation or acute illness may affect interpretation

However, research performed by doctors explains that when people can properly absorb and store vitamin B12, it is stored within the body for between 3 to 5 years

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A landmark study by Virta Health (2018) followed 262 type 2 diabetics on a supervised ketogenic diet for one year