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Its about restoring the signals that help your body regulate itself more effectively.
doi: 10.1038/s41419-023-05716-0 125 PulkkinenKHYl-HerttualaSLevonenAL
When to seek medical advice: Persistent or worsening injection site reactions (increasing redness, warmth, or discharge suggesting infection) Severe or persistent headaches Chest pain or palpitations Unexplained muscle weakness or cramps New or worsening neurological symptoms despite treatment Unexpected bleeding or bruising For non-emergency concerns, contact your GP or NHS 111
Clinical trials have found that the A 2A R antagonist istradefylline decreases dyskinesia in PD and could be used as an adjuvant to levodopa treatment
It works best as an adjunct combined with in-clinic treatments rather than on its own
