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FDA Registration No: 10-1-05061-5-0046
Calculated binding ratios between bound concentrations of CPP and immobilized peptide drugs at nasal absorption conditions revealed that binding ratios between L-penetratin and GLP-1 and exendin-4, respectively, were elevated when shuffle (R,K fix) 2 was used, indicating that the intermolecular interaction between CPP and cargo is critical for nasal peptide drug absorption (Khafagy et al., 2010b)
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