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For weight management, combining GLP-1 receptor agonists with other anti-obesity medications is generally considered off-label with limited evidence and should be directed by specialists
Those with a history of alcohol dependence should discuss whether weight loss injections are appropriate and receive support for maintaining sobriety
As a GLP-1 receptor agonist, semaglutide binds to GLP-1 receptors distributed throughout the gastrointestinal tract, pancreas, and central nervous system
10.1093/mp/sst080 38 ChenS.JiangH.CaoY.WangY.HuZ.ZhuZ.et al (2016)
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